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Media release: Statement from Dr Kerryn Symons, Country Medical Director, Roche New Zealand

Published 12 November 2025

Media release
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AUCKLAND Wednesday 12 November 2025 - Roche New Zealand welcomes today’s decision by Pharmac to fund OCREVUS® SC, PHESGO®, ROZLYTREK®, and VABYSMO® for some people living with cancer, multiple sclerosis, and eye disease.

Dr Kerryn Symons, Country Medical Director for Roche New Zealand, said:

“The decision to fund these treatments is an important step forward for patients and their whānau. We’re especially proud that this marks the first time a subcutaneous version of an intravenous cancer treatment will be publicly funded in New Zealand, alongside a subcutaneous version of a treatment for multiple sclerosis. Both innovations show how subcutaneous treatments can transform care by reducing treatment times and making it easier for people to fit their care around daily life. These treatments will provide more timely and convenient options for people living with cancer, multiple sclerosis, and eye disease. For many, that means less time in waiting rooms and treatment chairs, and more time with loved ones doing the things that matter most.

This decision will also ease pressure on our health system by freeing up valuable hospital and clinic capacity, allowing doctors and nurses to spend more time caring for people and supporting them on their treatment journeys.

I warmly congratulate Pharmac for funding these medicines. This milestone represents significant progress in improving access for New Zealanders, while also supporting the health system for the benefit of communities across Aotearoa.”

ENDS

Media contact

For more information, or to interview Dr Kerryn Symons, please contact:

Brooklyn Wheeler, Anthem

[email protected] - 027 346 0935

PHESGO® Consumer Panel

Phesgo® (pertuzumab and trastuzumab) 600 mg/600 mg and 1200 mg/600 mg solution for subcutaneous injection is a Prescription Medicine used for early breast cancer, either before or after surgery and for breast cancer that has spread to other parts of the body.

Ask your doctor if Phesgo is right for you.

Phesgo is a funded medicine for metastatic breast cancer for patients who meet defined criteria from 1 December 2025. A prescription charge and doctor’s fees apply.

Phesgo is an unfunded medicine for neoadjuvant or adjuvant treatment of early breast cancer. Ask your health professional about the cost of the medicine and other fees that may apply.

Use only as directed. If symptoms continue or you have side effects, see your healthcare professional. For more information about Phesgo:

Phesgo has risks and benefits.

Possible common side effects include: constipation, indigestion or stomach pain, sore mouth, throat or gut, fatigue or tiredness, getting tired more easily after light physical activity such as walking, shortness of breath especially when lying down or being woken from your sleep with shortness of breath, nail problems especially inflammation where the nail meets the skin, hair loss, feeling dizzy, tired, looking pale, hot flushes, frequent infections such as fever, severe chills, sore throat or mouth ulcers, nose bleeds, heartburn, eye problems such as producing more tears, insomnia (trouble sleeping), weak, numb, tingling, prickling or painful sensations mainly affecting the feet and legs, dry, itchy or acne like skin, loss of appetite, loss of or altered taste, joint or muscle pain, muscle weakness, sore throat, red, sore or runny nose, flu-like symptoms, and fever which may lead to infection of the ear, nose, or throat, pain at the injection site, reddened skin (erythema) and bruising at the injection site, general pain in the body, arms, legs and/or belly including sharp jabbing, throbbing, freezing or burning pain, feeling pain from something which should not be painful, such as a light touch, reduced ability to feel changes in temperature, loss of balance or coordination.

Do not use Phesgo if: you are pregnant or if you are allergic to pertuzumab, trastuzumab, or any of the ingredients in Phesgo.

Tell your doctor if: you have a history of heart problems such as heart failure, abnormal beating of the heart, poorly controlled blood pressure or have had a recent heart attack, you have previously been treated with chemotherapy medicines known as anthracyclines (e.g. doxorubicin) or radiation therapy (these medicines or treatment can damage heart muscle and increase the risk of heart problems with Phesgo), you take any medicines for any other condition, you are allergic to any other medicines or any other substances such as foods, preservatives or dyes.

Tell your doctor immediately or go to your nearest Accident and Emergency Centre if you notice any of the following signs and symptoms: allergic or anaphylactic reactions: including swelling of your face, lips, tongue or throat with difficulty breathing, or swelling of other parts of your body, shortness of breath, wheezing or trouble breathing, rash, itching or hives on the skin, feeling sick (nausea), fever or chills, headache or feeling tired; injection related reactions: these may be mild or more severe and may include feeling sick or vomiting, fever, chills, feeling tired, headache, loss of appetite, joint and muscle pains and hot flushes; heart problems: slower or faster heartbeat than usual, fluttering of the heart, abnormal or irregular heartbeat, cough, shortness of breath, swelling (fluid retention) in your legs or arms; tumour lysis syndrome (where cancer cells die quickly): kidney problems - signs include weakness, shortness of breath, fatigue and confusion, heart problems - signs include fluttering of the heart or a faster or slower heartbeat, seizures (fits), vomiting or diarrhoea and tingling in the mouth, hands or feet; severe chest pain: spreading out to the arms, neck, shoulder or back and diarrhoea: may be mild or moderate.

If you are pregnant or plan to become pregnant, PHESGO® may be harmful to an unborn baby. If there is a need for PHESGO® treatment when you are pregnant, your doctor will discuss the risks and benefits to you and the unborn baby. You should use effective contraception to avoid becoming pregnant while you are being treated with PHESGO® and for 7 months after stopping treatment.

If you become pregnant while receiving PHESGO®, or within 7 months following the last dose of PHESGO®, please contact your oncologist for medical advice. Report the pregnancy to Roche Patient Safety at [email protected] or 0800 276 243.

Additional information will be requested during a PHESGO®-exposed pregnancy and the first year of the infant’s life. This will enable Roche to better understand the safety of PHESGO® and to provide appropriate information to health authorities, healthcare providers, and patients.

For additional information, please refer to the PHESGO® Consumer Medicine Information at www.medsafe.govt.nz

Medsafe CMI

OCREVUS® Consumer Panel

OCREVUS® IV (ocrelizumab) 300mg vial, and OCREVUS® SC (ocrelizumab 920 mg/23 mL solution for subcutaneous injection) are Prescription Medicines used to treat relapsing forms of multiple sclerosis (RMS) and primary progressive multiple sclerosis (PPMS).

Ask your doctor if OCREVUS is right for you.

Ocrevus IV is a funded medicine when given as an infusion into the vein, for patients who meet defined criteria.

Ocrevus SC is a funded medicine when given as an injection under the skin, for patients who meet defined criteria from 1 December 2025.

Ask your health professional about the cost of the medicine and other fees that may apply.

Use only as directed. If symptoms continue or you have side effects, see your healthcare professional. For more information about Ocrevus:

  • Talk to your health professional; or

  • Visit medsafe.govt.nz for Ocrevus Consumer Medicine Information; or

  • Visit getonwithlife.co.nz or call Roche on 0800 276 243.

OCREVUS has risks and benefits.

Possible common side effects include: swelling of your face, lips, tongue or throat with difficulty breathing; swelling of other parts of your body; shortness of breath, wheezing or trouble breathing; skin problems including rash, itchiness or hives; feeling sick (nausea); fever, flushing or chills; cough, throat irritation or pain; feeling tired; headache; dizziness or light headedness; fast heartbeat.

Do not use Ocrevus if: you have had an allergic reaction to Ocrevus or any of the ingredients.

Tell your doctor if: you have an infection, or a history of a recurring or long-term infection such as hepatitis B; you are taking or have previously taken medicines which may affect your immune system, such as other medicines for MS you or your child intend to have or have had immunisation with any vaccine; you are allergic to any other medicines or any other substances such as foods, preservatives or dyes; you are pregnant or intend to become pregnant; you are breast feeding or plan to breast feed; if you are taking any other medicines, including any that you have bought without a prescription from a pharmacy, supermarket or health food shop; you notice any signs of an infection such as fever or chills, cold sore, shingles or genital sores; stuffy nose or chest; thick mucus in the nose, throat or chest; persistent cough; difficulty sleeping (insomnia); diarrhoea, vomiting and/or stomach cramps (gastroenteritis); skin infections, sinus infections.

Tell your doctor immediately or go to your nearest Accident and Emergency Centre if you notice any of the following: swelling of your face, lips, tongue or throat with difficulty breathing; swelling of other parts of your body; shortness of breath, wheezing or trouble breathing; local reaction at the injection site (Ocrevus SC only), skin problems including rash, itchiness or hives; feeling sick (nausea); fever, flushing or chills; cough, throat irritation or pain; feeling tired; headache; dizziness or light headedness; fast heartbeat.

Medsafe CMI

VABYSMO® Consumer Panel

VABYSMO® (faricimab) 120 mg/mL solution for injection for intravitreal use is a Prescription Medicine for the treatment of neovascular (wet) age-related macular degeneration (wet AMD), diabetic macular oedema (DMO) and macular oedema secondary to retinal vein occlusion (RVO).

Ask your doctor if VABYSMO is right for you.

From 1 December 2025 VABYSMO is funded for nAMD and DMO for patients who meet predefined criteria.

VABYSMO is not funded for RVO.

Ask your health professional about the cost of the medicine and other fees that may apply.

Use only as directed. If symptoms continue or you have side effects, see your healthcare professional. For more information about VABYSMO:

  • talk to your health professional; or

  • visit medsafe.govt.nz for VABYSMO Consumer Medicine Information; or

  • visit roche.co.nz or call Roche on 0800 276 243.

VABYSMO has risks and benefits.

Possible common side effects include: eye pain, burning, stinging, itching, redness, gritty or scratchy feeling; blurred, cloudy or decreased sharpness of vision or yellowing of colours; increased production of tears or watering eyes or eye discharge; a sensation that something is in your eye; moving spots (floaters) or shadows in your vision; small or distorted pupil.

Do not use VABYSMO if: you are allergic to faricimab. Always check the ingredients to make sure you can use this medicine; if you have or suspect you have an infection in or around your eye; if you have inflammation in or around your eye (may be indicated by pain and/or redness).

Tell your doctor if you: experience any problems during the treatment.

You may not see as well after you are given VABYSMO and after the associated eye examinations. This is temporary. Do not drive or use machines until your eyesight has returned to normal.

VABYSMO should not be used during pregnancy unless the potential benefit outweighs the potential risk to your unborn child.

Tell your doctor immediately or go to your nearest Accident and Emergency Centre if you notice any of the following: sudden vision loss or change in vision; signs of a possible eye infection or inflammation, such as worsening redness of the eye or blood in and around the eye, eye pain, increased eye discomfort, blurred or decreased vision, an increased number of floaters (small particles) in your vision, increased sensitivity to light; you experience signs of a stroke, such as weakness or paralysis of limbs or face or difficulty speaking.

Use only as directed. If symptoms continue or you have side effects, see your healthcare professional.

For more information about VABYSMO talk to your health professional; or visit medsafe.govt.nz for VABYSMO Consumer Medicine Information; or visit roche.co.nz or call Roche on 0800 276 243.

ROZLYTREK® Consumer Panel

ROZLYTREK® (entrectinib) 100mg/200mg capsules, is a Prescription Medicine used for the treatment of adult patients with ROS1-positive, locally advanced or metastatic (spreading) Non Small Cell Lung Cancer (NSCLC), and the treatment of adult and paediatric patients 12 years of age and older, with neurotrophic tyrosine receptor kinase (NTRK) fusion-positive locally advanced or metastatic solid tumours, where other treatments have not worked or are not suitable for you.

Rozlytrek is a funded medicine for ROS1+ NSCLC for patients who meet defined criteria. A prescription charge and doctor’s fees apply.

Rozlytrek is an unfunded medicine for NTRK solid tumours. Ask your health professional about the cost of the medicine and other fees that may apply.

Use only as directed. If symptoms continue or you have side effects, see your healthcare professional. For more information about ROZLYTREK®:

  • Talk to your health professional; or

  • Visit medsafe.govt.nz for ROZLYTREK® Consumer Medicine Information; or

  • Visit cancertreatments.co.nz or call Roche on 0800 276 243.

Rozlytrek has risks and benefits.

Possible common side effects include: feeling tired, pain including headache or head pain or joint or muscle pain or pain or discomfort in limbs or bones, fever, constipation, diarrhoea, feeling sick (nausea) or being sick (vomiting) or stomach pain, difficulty in swallowing, changes in taste, an abnormal or unpleasant sense of touch, numbness or weakness of the arms and legs, loss of muscle coordination or being unsteady when walking, symptoms of anaemia such as tiredness/headaches/being short of breath when exercising/dizziness/looking pale, weight gain, loss of appetite, dehydration, muscle weakness, bone fractures, lung infection, urinary tract infection, blurred vision, rash, swelling or puffiness of the skin, disturbances in your sleep pattern, red, hot, stiff or swollen joints.

Do not use Rozlytrek if: you are allergic to entrectinib or any of the other ingredients in this medicine, or if you or your partner are pregnant or you are breastfeeding. Do not take this medicine after the expiry date printed on the pack or if the packaging is torn or shows signs of tampering.

Tell your doctor if: you have allergies to any other medicines/foods/preservatives/dyes, you have heart problems such as a condition called ‘prolonged QT interval’ or a condition called 'congestive heart failure’ or ‘heart failure’, you have an inherited problem called ‘galactose intolerance’, ‘congenital lactase deficiency’ or ‘glucose-galactose malabsorption’, liver or kidney problems, or if you are planning a pregnancy or plan to breastfeed. Tell your doctor if you are taking any other medicines.

Tell your doctor immediately or go to your nearest Accident and Emergency Centre if you notice any of the following: signs of heart problems (heart failure) such as persistent coughing or wheezing, shortness of breath, and swelling in your legs or arms (fluid retention); feeling dizzy or light-headed as this may be a sign of an abnormal heart rhythm or low blood pressure; feeling confused, changes in mood, having memory problems or seeing things that are not there (hallucinations); loss of consciousness or fainting; symptoms of a condition called tumour lysis syndrome, including nausea or vomiting, muscle cramps or twitches, decreased urination, irritability, sudden uncontrolled fits (seizures).

Medsafe CMI

M-NZ-00001506/NOV2025